Role of organic carbon and nitrogen of mineral waters in their immunomodulating effects at female rats

Background. Drinking mineral water is one of the ethnopharmacologic factors. Organic substances, despite their presence in all drinking waters, are still considered to be active only Naftussya type (which, due mineralization less than 1 g/L, not formally mineral), whereas physiological activity true waters (which greater 1-2 g/L) associated with electrolytes and trace elements. Previously, we identified role organic carbon nitrogen effects on certain metabolic neuro-endocrine parameters. The purpose this study clarify substances same immunity Material methods. Experiment was performed 48 healthy female Wistar rats 240-290 g divided into 5 groups. Animals first group for 6 days administered a single tap through tube at dose 1,5 mL/100 body mass. In second from Truskavets’ layer (Galychyna, Ukraine), third Sophiya field. fourth received native Hertsa (Bucovyna, Ukraine) field, last its artificial salt analogue. day after completion course immunne parameters were registered. Results. On basis correlation analysis step-by-step exclusion, 9 immune (Endotheliocytes Thymus, Spleen Mass Index, Entropy Splenocytogram, Natural Killers, B- 0-Lymphocytes, Rod-shaped Neutrophils, Phagocytic Index Microbian Count Monocytes Blood) included regressive model (R=0,818) Fibroblastes Reticulocytes Spleen, Pan-Lymphocytes, Neutrophils (R=0,690). Together, components chemical composition loading fluids determine effect by 77%. Conclusion. play an essential rats.